Microarray Core Facility

Recent Publications

1 Xu A, et al. TGF-β-Induced Regulatory T Cells Directly Suppress B Cell Responses through a Noncytotoxic Mechanism. J Immunol. 2016 Mar 21 Anping Xu
2 Pathak S et al. Fatty Acid Amide Hydrolase Regulates Peripheral B Cell Receptor Revision, Polyreactivity, and B1 Cells in LupusJ Immunol. 2016 Feb 15;196(4) Pathak Simanta
3 Kramer J, et al. Analysis of IgM antibody production and repertoire in a mouse model of Sjögren's syndrome.J Leukoc Biol. 2016 Feb;99(2):321-31. Kremer Jill
4 Hasan M, et al. Cutting Edge: Inhibiting TBK1 by Compound II Ameliorates Autoimmune Disease in Mice J Immunol. 2015 Nov 15 Hasan Maroof
5 Wei JH, et al. A CpG-methylation-based assay to predict survival in clear cell renal cell carcinoma.Nat Commun. 2015 Oct 30;6:8699. Wei Jin-Huan
6 Gao D, et al. Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases.Proc Natl Acad Sci U S A. 2015 Oct 20 Gao Daxing
7 Hasan M, et al. Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation.Immunity. 2015 Sep 15;43(3):463-74. Maroof Hasan
8 Mayeux J, et al. Genetic Interaction between Lyn, Ets1, and Btk in the Control of Antibody Levels.J Immunol. 2015 Sep 1;195(5):1955-63. Jessica Mayeux
9 Huang QQ , et al. CD11c-mediated deletion of Flip promotes autoreactivity and inflammatory arthritis. Nat Commun. 2015 May 12:6:7086 Qi-Quan Huang
10 Shao X, et al. Inducible expression of kallikrein in renal tubular cells protect mice from spontaneous lupus nephritis.Arthritis Rheum. 2013; 65(3): 780-791 PMID: 23280471 Shao X, et al.
11 Gutierrez T, et al. IL-21 promotes the production of anti-DNA IgG but is dispensable for kidney damage in lyn-/- mice.Eur. J. Immunol. 2012. 43: 1–12 PMID: 23169140 Gutierrez T, et al.
12 Chong BF, et al. IgG and IgM Autoantibody Differences in Discoid and Systemic Lupus Patients. J Invest Dermatol. 2012;132(12):2770-9. PMID: 22763789 Chong BF, et al.
13 Xia Y, et al. The constant region contributes to the antigenic specificity and renal pathogenicity of murine anti-DNA antibodies. Journal of Autoimmunity 2012; 39: 398-411 PMID: 22841793 Xia Y, et al.
14 Li Y, Wang H, et al. Influence of Carbon Monoxide on Growth and Apoptosis of Human Umbilical Artery Smooth Muscle Cells and Vein Endothelial Cells. Int J Biol Sci. 2012; 8(10): 1431-46 Li Y, Wang H, et al.
15 Olsen NJ, et al. Autoantibody profiling to follow evolution of lupus syndromes. Arthritis Res Ther. 2012; 14(4): R174. Olsen NJ, et al.
16 Wu T, et al. Metabolic disturbances associated with systemic lupus erythematosus. PLoS One. 2012; 7(6):e37210. Wu T, et al.
17 Li L, et al. Murine lupus strains differentially model unique facets of human lupus serology. Clin Exp Immunol. 2012;168(2):178-85. doi: 10.1111/j.1365-2249.2012.04568.x Li L, et al.
18 Tan BK, et al. Evidence for intranasal anti-nuclear antibodies in Chronic Rhinosinusitis with Nasal Polyps. J Allergy Clin Immunol; 2011; 128(6):1198-1206.e1 PMID: 21996343 Tan BK, et al.
19 O'Neill SK, et al. Monophosphorylation of CD79a and CD79b ITAM Motifs Initiates a SHIP-1 Phosphatase-Mediated Inhibitory Signaling Cascade Required for B Cell Anergy. Immunity; 2011; 35(5):746-56 PMID: 22078222 O'Neill SK, et al
20 Dozmorov IM, et. Internal standard-based analysis of microarray data2--Analysis of functional associations between HVE-genes. Nucleic Acids Res. 2011 Oct 1;39(18):7881-7899 Dozmorov IM, et.
21 Su Z, et. Comparing next-generation sequencing and microarray technologies in a toxicological study of the effects of aristolochic Acid on rat kidneys. Chem Res Toxicol. 2011 Sep 19;24(9):1486-93. Su Z, Li Z, Chen T, Li QZ, Fang H, Ding D, Ge W, Ning B, Hong H, Perkins RG, Tong W, Shi L.
22 Xie Y. Robust gene expression signature from formalin-fixed paraffin-embedded samples predicts prognosis of non-small-cell lung cancer patients. Clin Cancer Res. 2011 Sep 1;17(17):5705-14 Xie Y,Xiao G, Coombes KR, Behrens C, Solis LM, Raso G, Girard L, Erickson HS, Roth J, Heymach JV, Moran C, Danenberg K, Minna JD, Wistuba II.
23 Stoll ML, et. Elevated IgG autoantibody production in oligoarticular juvenile idiopathic arthritis may predict a refractory course. Clin Exp Rheumatol. 2011 Jul-Aug;29(4):736-42. Stoll ML,Li QZ, Zhou J, Punaro M, Olsen NJ.
24 Quiat D,et. Concerted regulation of myofiber-specific gene expression and muscle performance by the transcriptional repressor Sox6. Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10196-201. Quiat D,Voelker KA, Pei J, Grishin NV, Grange RW, Bassel-Duby R, Olson EN.
25 Sunaga N, et. Oncogenic KRAS-induced interleukin-8 overexpression promotes cell growth and migration and contributes to aggressive phenotypes of non-small cell lung cancer. Int J Cancer. 2011 May 4. doi: 10.1002/ijc.26164 Sunaga N, et.
26 Kwak YT, et. Cells lacking IKKα show nuclear cyclin D1 overexpression and a neoplastic phenotype: role of IKKα as a tumor suppressor. Mol Cancer Res. 2011 Mar;9(3):341-9. Kwak YT, Radaideh SM, Ding L, Li R, Frenkel E, Story MD, Girard L, Minna J, Verma UN.
27 Li QZ, et al. Risk factors for ANA positivity in healthy persons. Arthritis Res Ther. 2011 Mar 2 Li QZ, Karp DR, Quan J, Branch VK, Zhou J, Lian Y, Chong BF, Wakeland EK, Olsen NJ.
28 Sunaga N, et. Knockdown of oncogenic KRAS in non-small cell lung cancers suppresses tumor growth and sensitizes tumor cells to targeted therapy. Mol Cancer Ther. 2011 Feb;10(2):336-46. Sunaga N, Shames DS, Girard L, Peyton M, Larsen JE, Imai H, Soh J, Sato M, Yanagitani N, Kaira K, Xie Y, Gazdar AF, Mori M, Minna JD.
29 Shi L, et. The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models. Nat Biotechnol. 2010 Aug;28(8):827-38. Epub 2010 Jul 30. Shi L, et.
30 Jeong Y, et. Nuclear receptor expression defines a set of prognostic biomarkers for lung cancer.PLoS Med. 2010 Dec 14;7(12):e1000378. Jeong Y, et.
31 Koh AY,et. Utility of in vivo transcription profiling for identifying Pseudomonas aeruginosa genes needed for gastrointestinal colonization and dissemination.PLoS One. 2010 Dec 10;5(12):e15131. Koh AY,et.
32 Renthal NE, et. miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor.Proc Natl Acad Sci U S A. 2010 Nov 30;107(48):20828-33. Epub 2010 Nov 15. Renthal NE, et.
33 Du L, et. MicroRNA expression distinguishes SCLC from NSCLC lung tumor cells and suggests a possible pathological relationship between SCLCs and NSCLCs. J Exp Clin Cancer Res. 2010 Jun 17;29:75. Du L, et.
34 Gutierrez T, et. Separate checkpoints regulate splenic plasma cell accumulation and IgG autoantibody production in Lyn-deficient mice. Eur J Immunol. 2010 Jul;40(7):1897-905. Gutierrez T, et.
35 Li QZ,et al. Interferon signature gene expression is correlated with autoantibody profiles in patients with incomplete lupus syndromes.Clin Exp Immunol. 2010 Mar;159(3):281-91. Epub 2009 Dec 1. Li QZ,Zhou J, Lian Y, Zhang B, Branch VK, Carr-Johnson F, Karp DR, Mohan C, Wakeland EK, Olsen NJ.
36 Reading NC, et al. A transcriptome study of the QseEF two-component system and the QseG membrane protein in enterohaemorrhagic Escherichia coli O157 : H7.Microbiology. 2010 Apr;156(Pt 4):1167-75. Epub 2010 Jan 7. Reading NC, Rasko D, Torres AG, Sperandio V.
37 Li QZ, et al. The lupus-susceptibility gene kallikrein downmodulates antibody-mediated glomerulongphritis. Genes & Immun, March 5 2009. doi:10.1038/gene.2009.7. Li QZ, Zhou J, Yang R, Yan M, Ye Q, Liu K, Liu S, Shao X, Li L, Zhou XJ, Wakeland EK, Mohan C.
38 Liu K, et al. Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans. J Clin Invest, 2009; 119(4): doi:10.1172/JCI36728 Liu K, et al.
39 Xie Y, et al.Statistical methods of background correction for Illumina BeadArray data. Nat Genet. 2008; 40(2): 204-10 Alarcón-Riquelme ME, Criswell LA, ...QZ Li
41 Hutcheson J, et al. Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity. Immunity. 2008;28(2):206-17 Scatizzi JC, Siddiqui AM, Haines GK 3rd, Wu T, Li QZ, Davis LS, Mohan C, Perlman H
42 Zhang H, et al. Elucidating a normal function of huntingtin by functional and microarray analysis of huntingtin-null mouse embryonic fibroblasts.BMC Neurosci. 2008 Apr 15;9:38 Zhang H, et al.
43 Zachariou V, et al. Distinct roles of adenylyl cyclases 1 and 8 in opiate dependence: behavioral, electrophysiological, and molecular studies. Biol Psychiatry. 2008 Jun 1;63(11):1013-21 Zachariou V
44 Shi L, et. The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies. BMC Bioinformatics. 2008 Aug 12;9 Suppl 9:S10. Shi L, Jones WD, Jensen RV, Harris SC, et.
45 Ding LH,et. Enhanced identification and biological validation of differential gene expression via Illumina whole-genome expression arrays through the use of the model-based background correction methodology.Nucleic Acids Res. 2008 Jun;36(10):e58. Epub 2008 May 1. Ding LH,et.
46 Li, QZ, et al. Protein array autoantibody profiles for insights into systemic lupus erythematosus and incomplete lupus syndormes. Clin Exp Immunol. 2007;147(1):60-70 Li QZ, Zhou J, Wandstrat AE, et.
47 The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements.Nat Biotechnol. 2006 Sep;24(9):1151-61. MAQC Consortium
48 Li, QZ, et al. Identification of autoantibody clusters that best predict lupus disease activity using glomerular proteome arrays. J Clin Invest. 2005;115(12):3428-39 Li QZ, Xie C, Wu T, Mackay M, Aranow C, Putterman C, Mohan C.